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Heritable and Social-Environment Risks for Substance Use

A study of 600 adolescent twin pairs in Southern California and another 600 twin pairs in Qingdao, China, that quantifies the nature of environmental influences and the extent to which they interact with genetic sources of variation in smoking-related behaviors.

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Effect Moderation and Mediation in Prevention Programs

An investigation of the effects that social, genetic, and neurocognitive underpinnings of dispositional characteristics — particularly hostility and depression — have on substance use uptake and progression, and how that moderates prevention and cessation program effects.

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Genetic Variants and Tobacco Use in Chinese Adolescents

A study focusing on genetic factors responsible for hostility, depression, and other dispositional attributes. It hypothesizes that these factors may have a significant influence on an individual’s progression toward increased smoking and on his or her responsiveness to tobacco control intervention and prevention programs.

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